EVALUATING THE CORRELATION OF LIPID PROFILE PARAMETERS INCLUDING TRIGLYCERIDES, VLDL, HDL, LDL, AND TOTAL CHOLESTEROL TO MEAN PLATELET VOLUME

Abstract

Background: The measurement of average platelet volume, or MPV, is essential for determining the presence of 
atherosclerosis. Clot retraction, procoagulant activity, secretion, aggregation, shape change and spreading, and 
adhesion are among the activities of platelets. Electrical impedance can be used by the ABX Pentra automated 
analyzer to assess MPV. Atherosclerosis is predicted by cholesterol levels.  
markers, 
such 
Aim: The purpose of the current study was to evaluate the relationship between mean platelet volume and lipid 
profile 
as 
triglycerides, 
VLDL, HDL, LDL, and total cholesterol.  
Methods: The link between lipid profile measures, such as triglycerides, VLDL, HDL, LDL, and total cholesterol, 
and mean platelet volume was examined in 48 research participants who had no history of platelet dysfunction, 
alcohol use, or medication-induced platelet decline. The gathered data were statistically assessed, and conclusions 
were drawn.  
Results: The study's findings indicate that there was an inverse relationship between mean platelet volume and 
HDL. Therefore, the techniques used to raise HDL will result in a lower MPV and a lower risk of atherosclerosis.  
Additionally, there was a positive but statistically insignificant connection between VLDL and MPV and 
triglycerides. There was an observed negative and non-significant association between MPV and total cholesterol 
and LDL. 
Conclusion: The current study, within its limits, finds that mean platelet volume and HDL showed a negative 
connection. Therefore, the techniques used to raise HDL will result in a lower MPV and a lower risk of 
atherosclerosis. Additionally, there was a positive but statistically insignificant connection between VLDL and 
MPV and triglycerides.