SALMONELLA TYPHI IN ENTERIC PERFORATION RISK FACTORS AND ITS ROLE

Abstract

Background: A bacterial infection caused by the Salmonella enterica serotype Typhi, typhoid fever is characterized by 
the subtle start of diarrhea, constipation, stomach pain, a severe headache, and a persistent fever in afflicted individuals.  
Aim: The purpose of this study was to evaluate the function of salmonella typhi and risk factors for intestinal perforation. 
Methods: During the specified study period, 240 patients of both genders and a mean age of 32.2 years were evaluated. 
Data from the Institute's medical records on the diagnosis of intestinal perforation and typhoid fever in the included 
participants was evaluated retrospectively. ICD (International Classification of Diseases) codes created especially for 
typhoid fever were used to identify the patients. 
Results: According to the study's findings, of the 240 subjects evaluated, 50.8% (n=122) were female and 49.2% (n=118) 
were male. The length of the illness prior to admission at the institute varied, with 35% (n=84) of the subjects presenting 
within 7 days of the onset of symptoms, 65% (n=156) had a longer illness duration, and the maximum disease duration 
was 21 days.  
Conclusion: The current study comes to the conclusion that it has successfully identified a number of important risk 
factors associated with the development of enteric perforation in individuals who had typhoid fever. These results 
highlight the critical role that early diagnosis and timely treatment play in reducing the likelihood of serious consequences.