EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF NARAVELIA ZEYLANICA LINN. LEAVES EXTRACT

Abstract

Naravelia Zeylanica Linn. commonly known as Vatnisini is traditionally used for several medicinal purposes in India. The present study assessed anti- inflammatory activity of its leaf. Dried and crushed leaves of Naravelia Zeylanica were extracted with ethanol. The ethanol extract (EENZ) at the doses of 250 mg/kg and 500 mg/kg body weight was subjected for evaluation of anti-inflammatory activity in experimental animal models.Acute anti-inflammatory activity was evaluated by Carrageenan, Histamine and Serotonon-induced paw oedema in Wister albino rats. Diclofenac sodium was employed as reference drug for anti-inflammatory study. In the present study, the ethanol extract of the leaves of Naravelia Zeylanica demonstrated significant acute anti-inflammatory activity in the tested models.