RECENTLY DISCOVERED IMMUNE THROMBOCYTOPENIA IN CHILDREN – AN ANALYTICAL STUDY

Abstract

Background: Evaluating immune thrombocytopenia (ITP) outcomes is critical in the Indian setting in order to get insight into the laboratory, clinical, and pathological variables that are associated with a higher risk of chronicity or illness persistence.
Aim: The purpose of this study was to evaluate the predictors and results of paediatric patients with recently diagnosed immune thrombocytopenia.
Methods: The study evaluated paediatric patients with newly diagnosed thrombocytopenia, ages ranging from 1 month to 18 years. Along with illness predictors and outcomes, laboratory, clinical, and pathological variables were evaluated in all included patients.
Results: Three participants were followed for three to twelve months, whereas 29 subjects had a minimum follow-up of one year. Study participants had an average age of 8.2±3.4 years, with 62.5% (n=20) being female. There was intracranial bleeding in 62.5% (n=10) and wet bleeding in 56.25% (n=18) of the individuals, respectively. There were 41.4% (n=12/29) and 65.6% (n=21/32) of participants with chronic and persistent ITP, respectively. At a year, ALC was 2.96 x103/μL and 3.99 x103/μL, respectively, in participants who had no reaction and those who had an overall response (p=0.03). The treated group had a nearly 10% lower reaction than the non-treated group.
Conclusion: The current investigation comes to the conclusion that there is a larger incidence of cerebral haemorrhage and chronicity than what has been documented in the literature. In individuals with thrombocytopenia, the response is correlated with higher absolute leucocyte counts.