DEXRABEPRAZOLE: A NEW EMERGING APPROACH IN TREATMENT OF GIT DISORDER

Abstract

Dexrabeprazole [R(+) rabeprazole] is a novel proton-pump inhibitor which is used in treatment of acid peptic diseases, gastroesophageal reflux disease (GERD) maintenance therapy, erosive esophagitis, short-term treatment of active duodenal and zollinger-ellison syndrome and treatment of H.Pylori-induced ulcers. This review explains superiority of dexrabeprazole (at half the recommended rabeprazole dose) over rabeprazole in terms of favourable pharmacokinetics, more efficacy, longer half-life, better healing of esophagitis, and fastly symptom control.