ASSESSING SERUM PROGESTERONE WITH REFERENCE INTERVAL DURING THREE TRIMESTERS OF NORMAL PREGNANCY IN WEST BENGAL FEMALES

Abstract

Background: For both the mother and the foetus, the hormonal milieu throughout pregnancy becomes a critical 
predictor. A certain hormone concentration evaluated at each trimester can be a good predictor of feto-maternal 
outcomes. The literature data indicates that because Indian pregnant women have distinct reproductive profiles from 
those of Western women, the reference of progesterone regarded normal in Western women may not apply to them.  
Aim: The purpose of this study was to evaluate the reference range for a trimester-specific progesterone test in 
healthy pregnant Indian women. 
Methods: The study comprised 138 pregnant women in good health who were in all three trimesters of their 
pregnancy. The included participants' blood progesterone levels were measured using an enzyme-linked 
immunosorbent assay (ELISA).  
Results: The current study's findings indicate that blood progesterone levels gradually rise during pregnancy. 
The current investigation reveals that there is a significant discrepancy between the progesterone values observed in 
healthy Indian girls and the defined reference range.