UV VISIBLE SPECTROPHOTOMETRIC ESTIMATION OF EMTRICITABINE

Abstract

A low cost precise spectrophotometric method has been developed for the estimation of Emtricitabine in bulk and tablet dosage form. Emtricitabine shows maximum absorbance at 298nm in presence of solvent chloroform and phosphate buffer of pH 7.4. The Beer’s law is obeyed in the concentration range of 2-20 μg/ mL and the graph of the drug shows a straight line with correlation coefficient of 0 .9910. The assay method of the drug was validated by accuracy and precision of the proposed method. The results are validated as per the directions of International conference on Harmonization