EVALUATION OF RISK STRATIFICATION FOR INDICATORS OF A POTENTIALLY DANGEROUS BACTERIAL INFECTION IN ORDER TO FORECAST NEWBORN DEATH

Abstract

Background: One of the leading reasons of newborn death is PSBI (possible severe bacterial infection). PSBI is separated 
according to clinical disease and serious infection indicators based on WHO data. By evaluating PSBI symptoms, newborns 
can be categorized into risk categories for proper care and prognosis. 
Aim: The purpose of this study was to evaluate the risk stratification of indicators of a potentially severe bacterial infection 
in order to predict death in babies ages 0-59 days.  
Methods: 440 newborns exhibiting symptoms of a potentially dangerous bacterial illness were evaluated for this 
investigation. These newborns, who ranged in age from 0 to 59 days, were split into two groups: those who showed symptoms 
of critical illness (CI) and Group II had subjects with signs of CSI (clinical severe infection). Each sign of PSBI was assessed 
for the correlation with mortality. Time of death was assessed using Kaplan Meier survival analysis.  
Results: 440 newborns were evaluated for illness outcomes. High death rates of 9% and 20% were linked to severe chest pain 
and low body temperature in CSI symptoms, whereas low mortality rates were linked to movement only upon stimulation, 
poor eating, rapid breathing, and fever. Convulsion, no movement at all, and no eating at all were linked to high death rates 
of 14%, 63.7%, and 47.4%, respectively, in relation to CI symptoms. Most fatalities were made public within 48 hours.  
Conclusion: Low body temperature, chest discomfort, and any indications of a significant bacterial infection are 
characteristics of newborns with a high death risk. Risk stratification based on clinical indicators can further lower infant 
death rates by prioritizing infants in need of immediate care.