EVALUATING THE CLINICAL-ETIOLOGICAL PROFILE OF HOSPITAL ACQUIRED DIARRHOEA IN PATIENTS UNDER THE AGE OF FIFTEEN: A CLINICAL EXAMINATION

Authors

  • Dr. Prateek Jaiswal Author

Keywords:

Bacterial infections,, Escherichia coli,, Enteropathogenic,, Hospital-acquired diarrhea.

Abstract

Background: Approximately 2-32% of children treated to hospitals get hospital-acquired diarrhoea (HAD), which 
raises hospital stays, costs, and death. Every HAD episode causes the youngsters to lose nutrients that are essential 
for their growth. Paediatric patients are more vulnerable in hospitals because of their contact with patients who have 
communicable diseases, medical personnel, and contaminated surfaces. Poor infection control raises the risk even 
further in low-income institutions.  
Aim: The purpose of the current clinical investigation was to evaluate the incidence and cause of paediatric patients' 
hospital-acquired diarrhoea.  
Methods: The 120 participants in this research were hospitalised for causes other than diarrhoea and ranged in age 
from 1 to 15 years. Their hospital stays lasted longer than three days. Stool samples were taken from each research 
participant and analysed to see whether any bacterial, viral, parasite, or fungal agents were present. The human 
rotavirus antigen was found using a latex agglutination test, while Clostridium difficile was found using an ELISA 
assay. 
Results: Of the 108 patients who had diarrhoea that they had acquired in the hospital, the majority (19.16%; n = 23) 
had Enteropathogenic Escherichia coli, followed by rotavirus (14.16%; n = 17), C. difficile (11.66%; n = 14), E. 
histolytica (10%; n = 12), and Pseudomonas aeruginosa (6.66%; n = 8). Shigella flexneri was detected in 5% (n=6) 
of the research patients, whereas the least amount of cases (n=3) of C. albicans, Giardia lambia, Cryptosporidium 
parvum, Proteus mirabilis, and Salmonella enteritidis were seen. 
Conclusions: According to the current study, paediatric patients experience hospital-acquired diarrhoea at a high 
rate, and the infectious aetiology was more common in these individuals than the non-infectious aetiology. The most 
frequent cause was an infection with germs.  

Published

02-02-2023

How to Cite

EVALUATING THE CLINICAL-ETIOLOGICAL PROFILE OF HOSPITAL ACQUIRED DIARRHOEA IN PATIENTS UNDER THE AGE OF FIFTEEN: A CLINICAL EXAMINATION . (2023). International Research Journal of Pharmacy, 14(2), 11-15. https://irjponline.org/index.php/irjp/article/view/7