TRENDS IN EMERGENCE OF ANTIBIOTIC RESISTANCE AND SENSITIVITY PATTERN OF COMMUNITY-ACQUIRED URINARY TRACT INFECTIONS IN TERTIARY CARE HOSPITALS OF SALEM DISTRICT, TAMIL NADU, INDIA
Keywords:
Antibiotic sensitivity, Urinary tract infection, Uropathogens,, Antibiotic resistanceAbstract
Background: To determine the trends in emergence of antibiotic resistance and sensitivity pattern and different types of organisms causing urinary tract
infections. Methods: A retrospective study was conducted at tertiary care hospitals of Salem district, Tamil Nadu, during November 2017-Apri 2018
and consisted of 600 patients of either gender between ages of 01-80 years. Results: Out of 600 adults, males were 309 (51 %) and females were 291
(49 %). E. coli (48.68 %) was the most common organism, followed by Klebsiella oxytoca (12.67 %), Enterococcus species (10.67 %), Klebsiella
pneumoniae. The incidence of UTI was more in patients in the age group of 01-15years. E. coli and Klebsiella oxytoca were sensitive to Amikacin,
Ampicillin, and Ciprofloxacin. All these organisms were resistant to Ceftriaxone. Conclusions: In this study, males were mostly affected and the most
common organisms were E.Coli and Klebsiella oxytoca. These organisms were most sensitive to Amikacin, Ampicillin, Ciprofloxacin, Imipenem and
resistant predominantly to Ceftriaxone. The sensitivity and resistance pattern of uropathogens to common antimicrobial agents must be taken into
account when selecting treatment plans for UTI.
