EFFECT OF THYROID REPLACEMENT THERAPY ON COGNITION IN HYPOTHYROIDISM PATIENTS

Abstract

The aim of the study was to evaluate the effect of thyroid replacement therapy on cognition in hypothyroidism patients using mini mental state
examination and to compare the cognitive status in hypothyroidism replacement therapy along with folic acid supplement. Prospective observational
study for the duration of 6 months was conducted. Among 120 subjects, 60 were prescribed with thyroid replacement therapy alone and the other 60
were prescribed with thyroid replacement therapy with folic acid supplement. The Cognition was improved in patients prescribed with folic acid
supplement along with thyroid replacement therapy. This study shows that the patients prescribed with folic acid supplement have good cognition level
rather than the patients prescribed with only hypothyroidism drug.