Design, Synthesis, Preformulation, and In Vitro Evaluation of Heterofenac SR: A Novel Heterocyclic NSAID Sustained-Release HPMC Matrix Tablet

Authors

  • Sakshi Sharma Author
  • Vinay Kumar Gupta Author
  • Sushant Kumar Sharma Author
  • Vipin Kumar Sharma Author
  • Aryarup Chakraborty Author
  • Snehal Praful Shingade Author
  • Ankita Vijay Thul Author
  • Yasmin Suthar Author
  • Muhammad Khursheed Author

DOI:

https://doi.org/10.56802/v7gfm431

Keywords:

Heterofenac,

Abstract

Background:
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for the management of pain and
inflammatory disorders; however, conventional immediate-release formulations often require frequent
dosing and may cause gastrointestinal adverse effects. Sustained-release drug delivery systems offer
improved therapeutic outcomes by maintaining consistent plasma drug concentrations. Heterofenac, a
novel heterocyclic NSAID, was developed to enhance anti-inflammatory efficacy and reduce dosing
frequency.

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Published

14-02-2026

Issue

Vol. 17 No. 2 (2026): Volume 17 Issue 2 2026

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Design, Synthesis, Preformulation, and In Vitro Evaluation of Heterofenac SR: A Novel Heterocyclic NSAID Sustained-Release HPMC Matrix Tablet. (2026). International Research Journal of Pharmacy, 17(2), 62-79. https://doi.org/10.56802/v7gfm431