EFFECTIVENESS OF RAMELTEON AND AGOMELATINE AS PREMEDICATION BEFORE ANAESTHESIA INDUCTION
Keywords:
Agomelatine, anaesthesia induction,, assessment of orientation,, ramelteon, pre-anesthetic medicationAbstract
Background Ramelteon is the first melatonin receptor agonist class medicine used in hypnotic therapy, and it was just
licensed by the FDA to treat insomnia. Melatonin MT2 and MT1 receptors are thought to help maintain heart rhythm and
regulate the sleep-wake cycle.
Aim: The current study sought to compare the effectiveness of Ramelteon and Agomelatine as premedication prior to
anaesthesia induction.
Methods: The research evaluated 120 ASA class I participants of both genders who had elective surgery under general
anaesthesia . These 120 participants were separated into two groups: Group I received Agomelatine, whereas Group II
received Ramelteon as a premedication prior to anaesthesia induction.