TARGETED DRUG DELIVERY THROUGH SOLID LIPID NANOPARTICLES AND ITS APPROACH: A REVIEW

Abstract

Solid lipid nanoparticles SLNs are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery,
research and clinical medicine as well as other varied science. Due to their unique size- dependent properties, lipid nanoparticles offer the possibility to
develop new therapeutics. Solid lipid nanoparticles (SLNs) consist of spherical solid lipid particles in the nanometer size range, which are dispersed in
water or in an aqueous surfactant solution. SLN technology represents a promising new approach to deliver hydrophilic as well as lipophilic drugs.
SLNs can also be used to improve the bioavailability of drugs. The incorporation of drugs into nanocarriers offers a new prototype in drug delivery that
could be used for several levels of drug targeting. Hence, solid lipid nanoparticles hold great promise for reaching the goal of controlled and site-specific
drug delivery and hence have attracted the wide attention of researchers. In the present review article focus on overview about the potential advantages,
disadvantages and all the different method involved in their production methodology, principle of drug release, evaluation and application.