STANDARDIZATION AND TOXICOLOGICAL EVALUATION FOR EFFICACY AND SAFETY OF PIMPINELLA ANISUM L.

Abstract

The demand of herbal medicine is increasing day by day due to their efficacy, safety (rare chances of side effects) in the treatment and good faith of society on herbal medicine and also their products. Therefore standardization and toxicological study of herbal medicine is quite necessary to check quality, Purity, strength and safety of the drugs. The present work is an attempt to evaluate toxicological parameters for safety of an herbal drug Pimpinella anisum L. such as microbial contamination, aflatoxins, pesticide residues and heavy metals. Additional standardization parameters like, physical constants, ash content, solvent residues, and microscopical analysis were also carried out and reported. The results obtained may be helpful to the regulatory authorities, scientific organizations and manufacturers for developing standards and maintaining the quality of drugs.