SPECTROPHOTOMETRIC ESTIMATION OF TERBUTALINE SULPHATE IN PHARMACEUTICAL DOSAGE FORMS

Abstract

A simple reproducible and efficient method for the determination of terbutaline sulphate in pharmaceutical dosage form has been developed using spectrophotometric method. The linear dynamic range was 4 to 20 mcg/ml with a coefficient of correlation 0.9993. The validity of the described procedure was assessed analytical parameters were calculate and a full statistical evaluation was performed. The proposed method was successfully applied to the determination of terbutaline sulphate in pharmaceutical formulations without any interference from common excipients. The reproducibility of the method is 99.87-100.66%.