WOUND HEALING ACTIVITY OF FLAVONOID FRACTION OF CYNODON DACTYLON IN SWISS ALBINO MICE

Abstract

The aim of the present study is to evaluate the wound healing activity of flavonoid fraction of Cynodon dactylon in swiss albino mice. The wound healing property of the fraction was studied in excision wound which was inflicted by cutting away 0.5cm standard full thickness of wound was created on the predetermined dorsal area. The flavonoid fraction of Cynodon dactylon were applied externally daily on the excised wound area for 8 days. This fraction facilitates the healing process as evidenced by increase in collagen and protein and decrease in lipid peroxide in granulation tissue. Thus, the enhanced wound healing may be due to free radical scavenging activity of the flavonoid fraction.