SCREENING OF MULTI DRUG RESISTANT ESCHERICHIA COLI FROM URINARY TRACT INFECTED PATIENTS

Abstract

Antimicrobial drug resistance is one of the major threats due to widespread use of antimicrobial drugs in general population and has been increasing in clinical significance over recent years. The prevalence of resistance to antibiotics by Escherichia coli is con current. A total of fifty samples were obtained from urinary tract infected patients, out of which 25 isolates of Escherichia coli were isolated and confirmed. All the strains were found to exhibit multiple antibiotic resistance patterns to eight antibiotics used. The present study was undertaken to accomplish isolation and characterization of multidrug resistant Escherichia coli and to assess the current resistant patterns of multidrug resistance among urinary isolates of Escherichia coli. 8 antibiotics were studied using disc diffusion Method. All the isolates were highly resistant to Tetracycline and resistant to Trimethoprim, Ofloxacin, Penicillin G, Amphicillin, Streptomycin and chloramphenicol. Many of the isolates were susceptible to Rifampicin, only 4% resistance was observed. The results demonstrate that the antimicrobial resistance of multi drug resistant Escherichia coli which may become endemic to the hospital environment day by day and may complicate the therapeutic management.