STUDY AT DIFFERENT CONCENTRATION OF POMGRANATE SHOWED ANTIAMOEBIC PROPERTIES INCASE OF AMOEBIASIS IN NIH MEDIUM

Abstract

Amoebiasis is the disease of large intestine or liver caused by Entamoeba histolytica. It is anaerobic parasitic protozoan, motile, commonly found in human intestine and it is also found in animals example like cat and goat but it's definitive host is human beings. It's Infective stage is quadric nucleated cyst is called trophozoite. Invasive intestinal amoebiasis is initiated with attachment of trophozoite to the colonic mucous layer and it starts the mucous disruption and depletion. Mucous secreted by fecal. Infection spread mainly by soiled hands, contaminated water and food or direct contact with carrier containing cysts of the protozoa. Man who has sex with man can also become infected. Approximately 50 million people have invasive disease resulting in 1, 00,000 death/year. After malaria it is the second severe disease because the parasite has a worldwide distribution so it is called worldwide disease. More than 10% of the population has been reported from various developing countries. A 1998 study in Africa suggests that 2 tablespoons per week of papaya seeds may have some antiamoebic action and aid in prevention of amoebiasis, but this remains unconfirmed. Papaya fruit and seeds are often considered beneficial to digestion in areas where this plant is common.