IN-VITRO STUDY OF ENTAMOEBA HISTOLYTICA WITH COCONUT JUICE ACT AS AN ANTIAMOEBIC AGENT AT DIFFERENT CONCENTRATION IN NIH MEDIUM

Abstract

Amoebiasis is a parasitic infection caused by Entamoeba histolytica. It is usually contracted by ingesting water or food contaminated with amoebic cysts. Amoebiasis is an intestinal infection that may or may not be symptomatic. When symptoms are present it is generally known as invasive amoebiasis. It is anaerobic parasitic protozoan, motile, commonly found in human intestine and it is also found in animals example like cat and goat but its definitive host is human beings. Its Infective stage is quadrinucleated cyst is called trophozoite. Invasive intestinal amebiasis is initiated with attachment of trophozite to the colonic mucous layer and it starts the mucous disruption and depletion. Mucous secret by fecal. Infection spread mainly by soiled hands, contaminated water and food or direct contact with carrier containing cysts of the protozoa. Man who has sex with man can also become infected. Approximately 50 million people have invasive disease resulting in 1, 00,000 death/year. After malaria it is the second severe disease because the parasite has a worldwide distribution so it is called worldwide disease. More than 10% of the population have been reported from various developing countries.