DESIGN DEVELOPMENT AND EVALUATION OF MODIFIED RELEASE TABLET OF MONTELUKAST SODIUM BY PELLETIZATION COMPRESSION AND TABLET COATING

Abstract

In this present study the pellets of the Montelukast sodium were prepared in the FBD which were compressed by using the MCC as the diluent. The compressed tablets were than coated with the coating polymer like Eudragit L and Eudragit S in the varying concentration. The dissolution of the tablets was carried out in the USP Basket apparatus and the drug release was studied for all the coated tablets.