SYNTHESIS AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF 1- BENZOYL-1H-PYRAZOLO [4,3-C]QUINOLIN-4(5H)-ONES

Abstract

A series of 1-benzoyl-1H-pyrazolo [4,3-C]quinolin-4(5H)-one, carrying appropriate substituents at the Quinoline ring have been synthesized in good yields via the condensation of 4-chloro-3-formylquinolin- 2[1H]ones with benzohydrazide using triethylamine as a base. All the synthesized compounds were evaluated for their antibacterial activities.