EFFICACY OF HISTOPATHOLOGY TO TVS/TAS IN DIAGNOSING THE ABNORMAL UTERINE BLEEDING: A PROSPECTIVE CLINICAL STUDY

Abstract

Background: Abnormal Uterine Bleeding (AUB) refers to any bleeding that deviates from normal in terms of 
volume, frequency, regularity, and duration. Menorrhagia, polymenorrhea, metorrhagia, and oligomenorrhea are 
some 
the 
words 
used 
to 
describe 
abnormal 
bleeding 
during 
menstruation.  
Aim: The current clinical study's goals were to evaluate the effectiveness of TVS/TAS and histopathological 
results in individuals with AUB. 
Methods: 102 participants with abnormal uterine bleeding between the ages of 21 and 85 made up this 
prospective clinical trial. In spite of baseline examinations and sonography results, all subjects received 
hysteroscopy, premenstrual dilatation, and curettage. Histological analysis was used to evaluate the acquired 
endometrial tissue.  
Results: The findings indicate that 3.92% (n=4), 12.74% (n=13), 2.94% (n=3), 32.35% (n=33), 51.96% (n=53), 
and 54.90% (n=56) of the study participants had cervical carcinoma, endometrial carcinoma, cervical polyp, 
endometrial polyp, adenomyosis, and myoma, respectively. The study's tissue findings were categorized as 
follows: 1.96% (n=2), 10.78% (n=11), 5.88% (n=6), 0.98% (n=1), 2.94% (n=3), 3.92% (n=4), 15.68% (n=16), 
11.76% (n=12), 25.49% (n=26), and 20.58% (n=21) subjects had cervical cancer, endometrial cancer, endometrial 
polyp, endometritis, atrophic endometrium, mixed, secretary, proliferative phase, endometrial hyperplasia, and 
normal epithelium, respectively.  
Conclusion: The current study concludes that transvaginal/transabdominal ultrasounds should be a regular part of 
assessment and examination procedures since they are a cost-effective primary assessment tool for the detection of 
AUB. Histopathologic examination is the gold standard in cases of non-gravid females with AUB, despite the fact 
that the diagnosis and treatment of the condition might be complicated.