ANTIMYCOBACTERIAL CHROMONE RHAMNOSIDE FROM MIMOSA PIGRA LINN. (FABACEAE) AERIAL PART

Abstract

Activity guided fractionation of the aerial part methanol extract of Mimosa pigra resulted in the isolation and characterization of a bioactive chromone rhamnoside (MIC; 0.5 mg/mL) as an anti-mycobacterial constituent. The structure of the bioactive chromone rhamnoside was elucidated using spectroscopic techniques to be 8-hydroxy-3-(phenyl)-4-benzopyrone-6-O- rhamnoside. This is the first report of anti-mycobacterial activity of Mimosa pigra and its potentials for the development of drug leads for the treatment of tuberculosis thus validating its uses in ethno-medicine.