A PROSPECTIVE STUDY TO IDENTIFY THE FACTORS CAUSING LEAK IN CASE OF SMALL BOWEL RESECTION AND ANASTOMOSIS USE OF CRP AS AN EARLY PREDICTOR OF ANASTOMOTIC LEAK AFTER GASTROINTESTINAL REPAIR SURGERIES
DOI:
https://doi.org/10.56802/hmv0by55Keywords:
Anastomotic Leak;, C-Reactive Protein (CRP);, Gastrointestinal Anastomosis;, Intestinal Resection;, Postoperative Complications;, Biomarker; Diabetes Mellitus;, Hypoalbuminemia, Early Prediction; Gastrointestinal Surgery.Abstract
Anastomotic leak is a major postoperative complication following gastrointestinal resection and
anastomosis, with risk factors such as diabetes mellitus, hypoalbuminemia, and impaired wound healing
contributing to its occurrence. This prospective observational study was conducted to identify factors
associated with anastomotic leak and to evaluate the role of postoperative serum C-reactive protein
(CRP) as an early predictive marker. A total of 100 patients undergoing gastrointestinal resection and
primary anastomosis were studied, and CRP levels were measured on postoperative days 1, 3, and 5.
Patients who developed anastomotic leak showed significantly higher CRP levels on postoperative days
3 and 5, while diabetes mellitus and hypoalbuminemia were found to be significantly associated with
an increased risk of leakage. Serial postoperative CRP monitoring was found to be a simple, reliable,
and cost-effective method for the early detection of anastomotic leak and may facilitate timely
intervention and improved surgical outcomes.
