CONJUGATED ESTROGEN AND PHYTOESTROGEN'S EFFECTS ON SURGICAL MENOPAUSE- A COMAPARATIVE STUDY

Abstract

Background: Vasomotor symptoms, which are more severe in surgical menopause, are short-term effects of 
menopause. Supplemental estrogen effectively reduces symptoms. Both estrogen and conjugated phytoestrogen are 
used to manage vasomotor symptoms. 
Aim: The purpose of this study was to evaluate the acceptability, safety, and effectiveness of phytoestrogen in reducing 
vasomotor symptoms in women undergoing surgical menopause in comparison to low-dose conjugated estrogen.
Methods: In six postoperative weeks, 128 female patients with surgical menopause and vasomotor symptoms were 
evaluated for this study. They were split into two equal groups at random. For 12 weeks, group I received 0.625 mg of 
conjugated estrogen daily, while group II received 100 mg of soy isoflavone daily. Subjects were asked to record the 
frequency and intensity of their vasomotor symptoms every day. Until the 12-week period was over, assessments were 
conducted every four weeks.