Capnography-Guided Sedation: Effects on Patient Safety and Recovery

Authors

  • Dr. Sudhanshu Sant Author
  • Dr. (Lt Col) Shama Vipin Jaishree Author
  • Dr. Manu Singh Author

DOI:

https://doi.org/10.56802/vsja7624

Keywords:

Capnography, Procedural sedation, Patient safety, End-tidal carbon dioxide, Respiratory monitoring, Recovery time

Abstract

Aim

The aim of this study was to evaluate the effect of capnography-guided sedation on patient safety and recovery outcomes during procedural sedation.

Methodology

This prospective randomized controlled clinical trial was conducted on 60 patients undergoing elective procedures under moderate sedation. Patients were randomly allocated into two groups. Group A (n = 30) was monitored using standard monitoring parameters along with continuous capnography, while Group B (n = 30) received standard monitoring alone. All patients were sedated using intravenous midazolam and fentanyl. Respiratory adverse events, time to detection of respiratory compromise, need for airway interventions, oxygen desaturation episodes, and recovery time were recorded and analyzed.

Results

The incidence of respiratory adverse events was significantly lower in the capnography group compared to the control group. Hypoventilation and apnea were observed less frequently in Group A. The mean time to detection of respiratory compromise was significantly shorter in the capnography group (18.4 ± 5.2 seconds) compared to the control group (54.6 ± 12.8 seconds; p < 0.001). Oxygen desaturation episodes and airway interventions were also significantly reduced in Group A. Recovery time was significantly shorter in patients monitored with capnography (21.3 ± 6.1 minutes) compared to the control group (32.8 ± 7.4 minutes; p < 0.001).

Conclusion

Capnography-guided sedation improves patient safety by enabling early detection of respiratory compromise and enhances recovery outcomes by reducing recovery time. Routine use of capnography during procedural sedation may significantly improve clinical safety and efficiency.

Downloads

Published

21-01-2026

How to Cite

Capnography-Guided Sedation: Effects on Patient Safety and Recovery. (2026). International Research Journal of Pharmacy, 17(1), 11-17. https://doi.org/10.56802/vsja7624