RELATIONSHIP BETWEEN SERUM BIOMARKERS AND METABOLIC PARAMETERS IN PATIENTS WITH SUDDEN HEART FAILURE

Abstract

Background: The prognosis of heart failure is greatly influenced by cardiac biomarkers, such as serum N-terminal pro B-type natriuretic peptide (NT-proBNP), which has been deemed the most accurate biomarker for heart failure diagnosis. There is a dearth of information in the literature about the relationship between hospital stay duration and cardiac biomarkers and biochemical measures in patients with acute heart failure.  
Aim: The purpose of this study was to evaluate the relationship between biochemical indicators and serum biomarkers in patients with acute heart failure. 
Methods: During the designated study period, 400 patients with acute heart failure diagnoses of both sexes from the Institute's Department of Cardiology were evaluated for this study. To measure serum potassium and NT-proBNP, blood samples from each individual were taken under very rigorous aseptic and sterile circumstances. A statistical analysis was performed on the collected data. 
Results: The length of stay for patients with acute heart failure was positively correlated with blood potassium and proBNP levels (p<0.05). With a mean value of pg/mL and a p-value of less than 0.05, the study's findings also demonstrated that serum NT-proBNP levels were highly significant over a week-long hospital stay. 
Conclusion: The current study comes to the conclusion that NT-proBNP and serum potassium are important biomarkers for determining morbidity in patients with acute heart failure as well as prognostic indicators. According to the current study, NT-proBNP and serum potassium estimation can also aid in the early prediction of hospital stay duration.