EVALUATION OF DENTAL CARIES, SALIVARY pH, AND THE ALTERATION OF TOOTH MICROBIALS IN CHILDREN WITH MUCOPOLYSACCHARIDOSIS

Abstract

Background: A class of lysosomal storage diseases known as mucopolysaccharidosis (MPS) is brought on by the
accumulation of polysaccharides within cells. This results in systemic and oral symptoms that are visible on radiographs and
in clinical settings.
Aim: The purpose of this study was to evaluate dental caries, salivary pH, and the alteration of tooth microbiota in children
with mucopolysaccharidosis.
Methods: In this study, 100 children with mucopolysaccharidosis were compared to 100 healthy controls who were between
the ages of 3 and 15. Saliva pH and an index of decaying, missed, and filled teeth as well as decayed filled and removed teeth
were measured and recorded for each patient.
In terms of microbiological analysis, saliva was inoculated into blood agar, Candida CHROMagar, MacConkey agar, and
Mitis salivarious agar. The CFUs (colony-forming units) were then measured and counted based on colony features and gram
staining.