DIRECT LARYNGOSCOPY AND INTUBATION ABSTRACT HEMODYNAMIC CHANGES AND THE IMPACT OF NALBUPHINE PREMEDICATION ON INTRAVENOUS CLONIDINE

Authors

  • Dr. Kishor Trikambhai Rupani Author
  • Dr Savita Gahalot Author
  • Dr Sudhir Kumar Singh Author
  • Dr Bhimani Shailesh Pachabhai Author

DOI:

https://doi.org/10.56802/kf148e90

Keywords:

premedication, nalbuphine

Abstract

Background: Proper premedication can be used to control abnormal changes in hemodynamic parameters during direct
laryngoscopy.
Aim: The purpose of this study was to compare and evaluate the effects of intravenous clonidine and nalbuphine
premedication on hemodynamic changes during direct laryngoscopy and intubations.
Methods: 58 research participants undergoing direct laryngoscopy were split into two groups of 29 at random. Group I
participants received clonidine (2 μg/kg), while Group II participants received nalbuphine (0.2 mg/kg) intravenously 10
minutes prior to the induction of anesthesia using a standard anesthesia technique. Changes in heart rates, blood
pressure, and ECG from baseline until after laryngoscopy and intubation, as well as at 1, 2, 3, 5, 10, and 15 minutes
after intubation, were evaluated. Additionally, side effects and complications were evaluated.

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Published

31-03-2021

Issue

Vol. 12 No. 3 (2021): Volume 12 Issue 3 2021

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

DIRECT LARYNGOSCOPY AND INTUBATION ABSTRACT HEMODYNAMIC CHANGES AND THE IMPACT OF NALBUPHINE PREMEDICATION ON INTRAVENOUS CLONIDINE. (2021). International Research Journal of Pharmacy, 12(3), 49-53. https://doi.org/10.56802/kf148e90